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doi: 10.3390/ijms25115874 159

It works on fat metabolism and weight loss

Hu, J., Webster, D., Cao, J., & Shao, A

Briefly, mice with a floxed allele of exon 5 Ppara were built up by using homologous recombination in ES cells and back-crossed with transgenic mice expressing Cre recombinase regulated by the albumin (Alb-Cre) promoters for at least eight generations to create hepatocyte-specific ( Ppara Hep ) knockout mice