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Nevertheless, SLC25A40 also transports GSH into the mitochondria and likely plays a secondary but important role

Hypotension, hypocalcemia, nausea, vomiting, and sneezing are the most common side effects of amifostine therapy [151], and switching to the subcutaneous route of amifostine at a 1000 mg dose is better tolerated with minor side effects in patients who are poorly tolerated with intravenous administration [152]

Rossing K, Christensen PK, Hovind P, Tarnow L, Rossing P, Parving HH

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A bone marrow aspirate (if done) would reveal erythroid hypoplasia with increased bone marrow iron (due to hepcidin-mediated sequestration and suppression of bone marrow erythropoiesis)