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NAA exerts its function in a histone acetyltransferase P300/CBP-associated factor (PCAF)-dependent manner, leading to lamin A acetylation, impairing its interaction with Sun2 (Sad1 and Unc84 domain-containing protein 2) and subsequent lytic granules, from CD8 + T cells and NK cells, polarization and release [214]

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Genes identified that reduce lipid accumulation include DGAT2 which functions in de novo lipogenesis

As TBA reacts also with several other aldehydes commonly present in the biological sample, the agents reacting with TBA are frequently denoted as thiobarbituric acid reacting species (TBARS)

Significant peptides were searched for biological pathway enrichment and parent protein interactions using the STRING database (Version 12) 34