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10.1371/journal.pone.0288523 83 JiangR.DuX.LnnerdalB

Serotonin is a neurotransmitter found primarily in thegastrointestinal tract, platelets and central nervous system

189 Multiple tissue-derived tumor samples show a large number of Arg1-positive myeloid cells in the tumor microenvironment

Vitamin A supports ocular surface repair and maintenance (Samarawickrama et al., 2015), and Vitamins C and E, both potent antioxidants, help alleviate symptoms of DED by reducing oxidative stress (Huang et al., 2016)

The effects of melatonin are mediated by two types of G-protein-coupled receptors (MT1 and MT2) located in various parts of the brain and peripheral tissues, such as the liver, pancreatic and cells, adrenal glands, blood vessels, and gonads [75]