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While studies on this population are limited, phentermine use during pregnancy has been associated with a risk of pulmonary hypertension a rare but serious lung disorder

[DOI] [PubMed] [Google Scholar] Huang T, Zhang K, Sun L, et al

Most real-world practice trends toward under-PEEPing, unknowingly leaving the lung on the left limb of the curve, where hidden derecruitment injury accumulates breath by breath

It's been studied in academic settings, but hasn't undergone the clinical trials required for drug approval in the United States