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The average age of those affected with konzo was 9.4 2.6 years, with samples taken from 14 Males and 15 Females

This condition is prevalent in about 8% of adult women, although it isnt talked about much.[ref] Animal studies show certain preservatives often used in body washes and shampoos can cause increased vaginal mast cells and eosinophils and had higher serum Immunoglobulin E

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Primer Auton Nerv Syst

Therefore, mutation of voltage-gated Na + , associated neuronal hyper-excitability, and imbalance of excitatory/inhibitory circuit can reduce seizure threshold leading to the development of epilepsy (Fig