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Description

When the binding sites of Keap1 are fully occupied by Nrf2, the newly produced Nrf2 translocates into the nucleus and induces the transcriptional activation of target genes that contain antioxidant response elements (AREs) in their regulatory regions (Yamamoto et al

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The study was conducted in accordance with the Declaration of Helsinki

The metabolomic data have been uploaded to the MetaboLights database under the following accession numbers: MTBLS12571 (serum), MTBLS12579 (muscle), MTBLS12580 (fat), and MTBLS12583 (liver)