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In vitro results demonstrated a significant enhancement of tumor cellular uptake, excellent mitochondria damage ability and improved antitumor efficiency of the multifunctional enveloped MSN

By controlling the miR-381-3p/E2F transcription factor 3 (E2F3) axis, EXOs lncRNA deleted in lymphocytic leukemia1 (DLEU1) generated from endometrial malignancies enhanced the migrative and invasive capabilities of endometrial cancerous cells (Jia et al., 2020)

10.3904/kjim.2014.29.3.291 220 YoonH

Additional research considerations include characterizing whether the enhanced membrane permeability of the acetylated form alters tissue distribution in in vivo models, whether the modified charge distribution affects receptor or chromatin binding dynamics, and whether the extended half-life requires adjusted concentration protocols in cell culture systems