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Smoking and IBS Why Cigarettes Can Make You Poop ?, 1.Nicotine is a stimulant: It activates the enteric nervous system (your guts second brain), which can speed up colon contractions and lead to a bowel movement., Does Smoking Cause Constipation? Gut Health Explained Nicotine and Digestion: Does Nicotine Make You Poop? GoodRx Do Cigarettes Make You Poop? Research, Digestive Effects & More
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