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One review found that B6 may be especially helpful for premenopausal women with depression, and the authors recommended further research into B6 as a therapy for hormone-related depression in women

Dong D, Zielke HR, Yeh D, Yang P

[DOI] [PubMed] [Google Scholar] 215.Spasovski G

Astrocytes release free fatty acids (FFAs) from lipid droplets, and the released fatty acids enter the mitochondria and bind to carnitine to form LCACs, the accumulation of which leads to mitochondrial dysfunction in astrocytes and exacerbates neuronal damage [115]

By delivering quantitative data on the carnitine and acylcarnitine pool, researchers can monitor how interventions affect fatty-acid transport, mitochondrial energy yield and amino-acid catabolism