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SwissADME-based prediction of drug-likeness and ADMET parameters The selected compounds were comprehensively evaluated for their physicochemical properties, pharmacokinetic profiles, drug-likeness parameters, and medicinal chemistry characteristics through the SwissADME computational platform developed and maintained by the Molecular Modeling Group at the Swiss Institute of Bioinformatics ( o/w ) by combining physics-driven approaches such as iLOGP, which reduces the overfitting tendency, with data-centered models trained on extensive experimental measurements

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Investigations have also identified a direct correlation between cortisol levels and dyslipidemia (307), further linking altered lipid profiles to depression