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Disclosures: Liam Swain: Nothing to Disclose, Jenny Godley: Nothing to Disclose, Meng Wang: Nothing to Disclose, Jennifer Flemming: Nothing to Disclose, Mayur Brahmania: Nothing to Disclose, Juan Abraldes: Gilead: Grant/Research Support, 89bio: Consultant, Boston Pharmaceuticals: Consultant, Novo Nordisk: Consultant, Boehringer Ingelheim: Consultant, Astra Zeneca: Consultant, Agomab: Consultant, Terumo: Speaking and Teaching, Cook: Grant/Research Support, Karen Tang: Nothing to Disclose, Abdel Shaheen: Nothing to Disclose 1549 THE EFFECT OF AREA-LEVEL MATERIAL AND SOCIAL DEPRIVATION ON CIRRHOSIS AND ALCOHOL-RELATED HEPATITIS HOSPITALIZATION RATES DURING THE COVID-19 PANDEMIC: A POPULATION-BASED STUDY Liam Swain Abdel Shaheen 1 Meng Wang 2 Jennifer Flemming 3 Mayur Brahmania 1 Juan Abraldes 4 Karen Tang 1 Jenny Godley 1 , 1 University of Calgary, 2 Alberta Health Services, 3 Queen's University Cancer Research Institute, 4 University of Alberta Background: Few studies have examined the impact of the COVID-19 pandemic on hospitalization rates for alcohol-related cirrhosis/hepatitis (AC/AH) and non-alcohol-related cirrhosis (NAC) in relation to the social determinants of health

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Similarly, inhibition of mTOR reduces the levels of glycine, asparagine, glutamine, and proline, all of which are essential for fibroblast activation and matrix deposition [111]

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Administer the dose as soon as remembered unless the next scheduled dose is imminent