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151 Paracellularly, following gliadin digest binding to its CXCR3 receptor, increased zonulin levels compromise tight junction function by activating the EGFR-PAR2-MyD88-mediated signaling pathways, resulting in increased intestinal permeability

Another key action of BPC-157 is its ability to promote angiogenesis, or the formation of new blood vessels

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Wagner et al., 2015)

Knezevic et al., 2021a), or by intragastric application of absolute alcohol (Gojkovic et al., 2021b) and intraperitoneal application of lithium overdose (Strbe et al., 2021)