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MTHFR C677T variant effects on homocysteine and glutathione GSH synthesis in the human RBC. The metabolite labels denote: Cys, Download Scientific Diagram Sustained dysregulation of iron and glutathione homeostasis induces chronoferroptosis, a persistent ferroptotic adaptation in neuronal cells Cell Death Discovery CBS and supplementing with NAC [N AcetylCysteine] ** People with a FAST CBS enzyme likely do NOT need more NAC. People with SLOW CBS likely do need more NAC. **PICTURE: CBSTranssulfuration Pathway starts Sulfur amino acid metabolism in autism spectrum disorder

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