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Modulating the expression of specific genes involved in collagen synthesis and tissue regeneration promotes firmer and healthier skin while supporting overall cellular health

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Oral administration of rhein (150 mg/kg in water) for 40 days significantly increased energy expenditure, reduced body weight, particularly body fat content, improved insulin resistance, and lowered circulating cholesterol levels in DIO mice

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As it was mentioned before, heme and ferrylHb are potent triggers of neutrophil infiltration (85)