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Every drug of abuse, including nicotine, releases dopamine, which makes it pleasurable to use and when you stop smoking, you have a deficiency of dopamine release, which causes a state of dysphoria: you feel anxious or depressed

These drugs cause euphoria by flooding the brain with chemical neurotransmitters such as dopamine and are highly addictive once a tolerance develops

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One reason for the development of the industry was the imposition of a state tobacco monopoly in the Ottoman Empire, a measure designed to increase Ottoman government revenue

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