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It has been shown that lysine supplementation dose-dependently reduced concentrations of all essential amino acids and adversely affected the growth of rats [101]

Takasu N, Takara M, Komiya I

3.2 Calcineurin inhibitors Calcineurin inhibitors are a class of immunomodulatory agents that play a crucial role in the regulation of immune responses by targeting specific intracellular pathways within T-lymphocytes