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Management of HPA typically involves dietary restrictions to limit phenylalanine intake and supplementation with BH4 or its precursor to restore enzyme activity

9 6 T match set

The eukaryotic kinase domain consists of twelve sub-domains with conserved amino acid residues necessary for regulation of kinase activity through binding ATP complexed to divalent cations (e.g., Mg 2+ or Mn 2+ ), the phospho-transfer reaction, and internal residues critical for proper protein folding(81)

Electronic Supplementary Materials Clinical Cases Clinical Cases Case 16.1 A 23 year old male is brought to the Emergency Department by the police