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[79], this review discusses how ferroptosis can enhance the sensitivity of tumor cells to radiation, potentially improving outcomes in head and neck radiation therapy

Teng, H., Yang, B., Su, Y., Chen, J., Cui, L., Sun, R., et al

Notably, improvements in endocrine parameters, such as elevated sex hormone-binding globulin (SHBG) levels and reduced total testosterone, have also been observed 375,379 , supporting the potential of probiotics in endocrine regulation

The DBA/2J mouse strain, which develops a similar phenotype of chronic glaucoma, has mutations in the Gpnmb gene (encoding a lysosomal-related glycosylated protein) and the Tyrp1 gene (encoding a melanosomal protein with possible enzymatic and structural functions) (38, 39)

Elevated levels of cytokines, such as TNF- and IL-6, disrupt the testicular microenvironment, affecting nutrient supply and metabolic balance essential for sperm production [67]