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Symptoms of vitamin B-12 deficiency include: Fatigue Difficulty concentrating Decreased mood Loss of appetite Poor memory Constipation Higher-risk groups for vitamin B-12 deficiency include people with intestinal disorders such as Crohns or Celiac disease, as well as those who suffer from muscular degeneration, Lou Gehrigs disease or diabetes

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Recent preliminary findings have demonstrated that triple-negative breast cancer (TNBC) cell lines had significantly higher NNMT levels than estrogen receptor-positive cell lines

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