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Free radical damages can accumulate over time and may thereby contribute to cell injury and development of human diseases

Expert Opin Pharmacother 5:13851398 Peters JU, Kuhne H, Dehmlow H, Grether U, Conte A, Hainzl D et al (2010) Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: optimization of in vitro activity

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