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Individuals on blood pressure medication should monitor their response carefully

One in vivo comparison of GHK versus GHK-Cu in rat experimental wounds found that GHK alone had no effect, and only the copper-bound GHK-Cu form produced a statistically significant increase in collagen accumulation evidence that the copper ion itself, not the peptide backbone alone, may be responsible for much of the collagen-stimulating activity

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Higher-concentration therapeutic formulations require a physicians prescription from a licensed compounding pharmacy

10.1155/2021/9924314 85 LiuM.ChuJ.GuY.ShiH.ZhangR.WangL.et al (2017)