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Description

Katzman MA, Bleau P, Blier P, et al

Pharmacokinetic and pharmacodynamic properties of cemdisiran, an RNAi therapeutic targeting complement component 5, in healthy subjects and patients with paroxysmal nocturnal hemoglobinuria

The calculated HBs and graphical depictions of HB interactions during a 100-ns simulation period are shown in Fig

Dose Range: 200600 mcg, using a gradual step-up approach

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