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Inhibition of lipogenesis AOD-9604 not only breaks down existing fat, but also brakes the formation of new fat

Upon ligand binding, the nanoparticle-receptor complex is internalized via clathrin-coated vesicles to be transported across the BBB and subsequently released by exocytosis into the brain parenchyma 119,120

In addition, allicin also has good immunoregulatory activity, which can activate the MAPK and SAPK/JNK pathways of Mtb -infected mouse peritoneal macrophages to produce various effector molecules, especially inducing an increase in IL-1 and IL-12