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Upon activation, conventional B cells (usually called B2 cells) differentiate into plasma and memory B cells

ZH: funding acquisition, conceptualization, supervision, writingreview and editing

Chronic low-grade inflammation (inflammaging) is increasingly recognized as a driver of age-related disease, and BPC-157s ability to modulate inflammatory pathways may have broader implications for healthy aging

Glutathione peroxidase (GPX) activity measurement The serum GPX activity was further confirmed based on the proteomics and PRM results in line with the GPX Assay Kit instructions (S0058, Beyotime, Haimen, China)

The APP(V642I) KI mouse model was engineered by introducing the V717I mutation into exon 17 of the mouse APP gene using homologous recombination and the Cre-loxP system