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doi: 10.1038/s41564-024-01794-8 85 LiuY.FillerS

Another prospective study demonstrated that the same reduced functional variants of OCT1 (M420del, R61C, G465R, and G401S) were linked to trough concentrations of metformin and progress in HbA1c post 6 months of metformin treatment in a group of 151 diabetic patients in South Danish cohort (Mahrooz et al., 2015)