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It binds to toll-like receptors (TLRs), specifically TLR4, which are expressed on numerous immune cells like macrophages, neutrophils, and dendritic cells (Wicherska-Pawowska et al., 2021)

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However, it simultaneously reduces the stability and diversity of the rumen microbial ecosystem, which may explain why the final body weight of calf yaks did not show significant changes

These studies have also clarified that formulas, botanical drugs, and active metabolites can help improve intestinal mucosal damage and alleviate LPS leakage

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