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This is not a formal ceiling because no FDA-approved limit exists, but it represents the upper range of what is supported by preclinical scaling and provider experience

The Institute of Medicine has not established a tolerable upper intake level of B12 because studies show no adverse health effects when taking excess levels of B12, either through food or supplements

A Cochrane Review of three randomized trials found that high oral doses of 1,000 to 2,000 mcg normalized serum B12 about as well as intramuscular injections

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Its superior formulation prevents it from shining through or discoloring paint, ensuring a flawless finish