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A lack of it can cause tiredness, changes in the nervous system, and megaloblastic anemia

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The bupropion component can increase seizure risk, particularly in patients with eating disorders, head trauma, or alcohol withdrawal

Severe or persistent diarrhea defined as more than six loose stools daily lasting beyond 48 hoursrequires clinical assessment to prevent complications and rule out alternative causes unrelated to the weight loss medication

have demonstrated that GADD45 was downregulated in multiple clinical datasets and in a murine MASLD model, where its expression mitigated lipid accumulation and insulin resistance in high-fat diet (HFD)-induced disease 6