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Willeke P, Schotte H, Schlter B, Erren M, Becker H, Dyong A, et al

In the human reference genome, there are seven GST gene families, each likely formed by gene duplications, and thus similar to each other in sequence and chromosomal location [18]

Neuroleptic malignant syndrome is a life-threatening neurologic emergency caused by central dopamine receptor blockade in the hypothalamus and nigrostriatal pathways

A more credible translational narrative for PF in DPN will therefore depend on (i) clarifying the active molecular entity and DPN-contextualized exposure, (ii) improving methodological rigor and model relevance, and (iii) linking exposure to disease-modifying structural and functional outcomes using clinically meaningful measures

30 Initially, HIF-1 activates lactate dehydrogenase A (LDHA) and glucose transporters to facilitate the transformation of the metabolic pathway from oxidative to non-oxidative carbon metabolism as well as ATP-producing pathways (glycolysis)