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10.1007/BF00626285 90 SakellariouG

Co-culturing ferroptotic cancer cells with dendritic cells (DCs) reveals that ferroptotic cells decrease maturation of DCs and dampen antigen cross-presentation, and hence inhibit adaptive immune response and promote tumor growth [232]

13,196 Spironolactone can also cause electrolyte imbalance and dehydration

The association of APR-246 with induction of ferroptosis (either by pharmacological compounds, or genetic inactivation of SLC7A11 or GPX4) had a synergistic effect on the promotion of cell death, both in vivo and ex vivo

In this study, we found that the NF-B pathway is activated in SGNs after peroxynitrite treatment and that the inhibition of NF-B pathway contributes to promote SGNs survived from peroxynitrite injury