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JAMA 328 , 12521255 (2022)

10.1016/j.freeradbiomed.2018.02.025 248 YangX.YuD.-D.YanF.JingY.-Y.HanZ.-P.SunK.et al (2015)

Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor, with high morbidity and mortality

However, in view of the excellent safety profile of B12, even at high doses, supplementation, ideally as part of a more comprehensive nutritional programme, may still be of value when the clinical picture and/or other factors (e.g