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According to the large-scale retrospective analysis of the Adjuvant Colon Cancer Endpoints (ACCENT) database, patients at least 70 years of age accounted for only 17.1 % of all cases [6], which was much lower than expected

Detoxification Research: Cofactor in glutathione peroxidase and transferase pathways

Production of tumor necrosis factor alpha and interferon gamma in interleukin-2-treated melanoma patients: correlation with clinical toxicity

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Dembinski A., Warzecha Z., Ceranowicz P., Tomaszewska R., Stachura J., Konturek S.J., Konturek P.C

Glutathione peroxidase catalyzes reactions in which the enzyme reduces hydrogen peroxide to water, as well as organic hydroperoxides (ROOH) to hydroxy derivatives, resulting in the conversion to the oxidized disulfide form GS-SG: H2O2 + 2GSH = GS-SG + H2O ROOH + 2GSH = GS-SG + ROH +H2O Glutathione peroxidase neutralizes peroxynitrite: ONOO- + 2GSH N2- + GSSG + 22 Glutathione reductase is a flavoprotein with a flavin adenine dinucleotide prosthetic group and consists of two identical subunits