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Cell viability assay The cytotoxicity of TB m A, TB m A-Glu, TB p A, and TBpA-Glu against human cancer cell lines (HepG2 and HeLa) and normal liver cell line (LO2) was measured by MTT assays as previously described 46

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In individuals with CHD, a reduction in oxidative stress (Reference Ju, Li and Li7) , a decrease in glycated Hb (HbA1c) and regulation of seven genes involved in insulin signalling (Reference Jablonska, Reszka and Gromadzinska8) were also noted after Se supplementation