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Tannins have been shown to reduce oxidative damage to lipids, proteins, and DNA, contributing to their protective effects against various diseases [217]

The diagnosis is established by: Low activity of gamma-glutamylcysteine synthetase in red blood cells, leukocytes and/or cultured skin fibroblasts

The Lancet 392(10146):508520

Median reduction in MRI-PDFF was 42% and 52% in the paired biopsy population at resmetirom 80mg and 100mg

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