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In OC, laminininduced LPA production and an LPAR3PI3K autocrine loop enhance migration despite the spatial relationships underlying LPA and laminins within the OC TME

Although not always elevated, intraocular pressure (IOP) remains the leading cause of irreversible blindness in patients with glaucoma [3]

Additionally, thiamines effects on prostaglandins, reactive oxygen species, cyclooxygenase-2, matrix metalloproteinases, and nitric oxide synthase have been linked to cancer (89)