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[7] That preclinical promise carried the compound into a human Phase II program for postoperative ileus but the randomized, placebo-controlled trial in bowel-resection patients did not meet its primary efficacy endpoint, and clinical development was subsequently discontinued

K.et al

The strongest predictors are baseline IGF-1 level, age, sleep quality (7-9 hours nightly), training consistency (4-6 days/week), diet quality, and protocol adherence

First, never introduce two new variables at once

Differences in mucus properties between patients, such as moisture level and renewal rate should be carefully evaluated because they affect therapeutic efficiency