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In summary, while PEFs hold transformative potential, addressing these practical hurdles through sustained research and technological refinement is essential for advancing their clinical adoption

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Drug elimination is the mirror image: it normally takes 3 5 half-lives for a drug to be eliminated from the plasma

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The mechanism could work in humans, or it might not

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The absence of FDA approval means no verified manufacturing standards, dosing protocols, or safety benchmarks exist for human use

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10.1016/j.bbr.2016.08.037 Behav

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