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First described back in the 1950s, acne erupts in about one in ten people within days or even hours of getting an injection of vitamin B12, which then disappears rapidly when injection treatment is discontinued. At the time, we had no idea what the mechanism might be, and the problem remained unsolved until just a few years ago when we finally figured it out: Vitamin B12 modulates the gene expression of the skin bacteria that cause acne

In reporter and cell assays, SLU-PP-332 is active at sub- to low-micromolar concentrations

Based on landmark studies, it has been shown to decrease headache duration, intensity, and frequency by 60% at the 6 months mark (which is 2 cycles of Botox)

The following chart outlines both the recommended daily intake (RDI) and tolerable upper intake levels (UL) for fat-soluble and water-soluble vitamins ( Due to potential toxicity, its not recommended to consume more than the tolerable upper intake levels set for the nutrients listed above