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[1] Smoking is primarily practiced as a route of administration for psychoactive chemicals because the active substances within the burnt, dried plant leaves (or other chemical) can vaporize into a gaseous state and be delivered into the respiratory tract, where they are rapidly absorbed into the bloodstream through the lungs and can reach the central nervous system

On the flip side, cheaper tobacco cigarettes can taste harsh or overly chemical, as though someone decided to throw in a splash of disappointment for good measure

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1 2 "Matthew Perry's Assistant and Doctors Charged With Getting Him Ketamine"