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To validate that this synergistic interaction is indeed dependent on mut-p53 and SLC7A11 expression, we next demonstrated that these drug combinations were more effective in H1299 cells overexpressing mut-p53 compared to the p53 Null parental line (Fig

found that methylenetetrahydrofolate reductase (MTHFR) deficiency causes DNA methylation in mouse sperm, and a large amount of DNA methylation loss was observed in both F1 and F2 sperm, and 80% of the sites may be passed on to the offspring

In biological matrices, approximately 99% of IGF-1 in blood is bound to six IGF-1 binding proteins (IGFBPs), while IGF-2 binds and interacts with IGF-1 receptor, IGF-2 receptor, IGFBP3 and transferrin

an optimistic approach for the treatment of inflammatory bowel disease

Ye Q, Zeng X, Cai S, Qiao S, Zeng X (2021) Mechanisms of lipid metabolism in uterine receptivity and embryo development