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An impure product could be contaminated with a whole host of disastrous things: leftover synthesis reagents, bacterial endotoxins, ormost relevant to our discussionother hormonally active substances

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Acetone carboxylase is the key enzyme of bacterial acetone metabolism in Xanthobacter autotrophicus strain Py2, catalyzing the ATP-dependent carboxylation of acetone to form acetoacetate [22]