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Statistical analysis was performed in R (v4.0) environment and MetaboAnalyst R (v3.0)

The combination of AZD6234 with other incretin-based agents, such as the GLP-1/glucagon dual agonist AZD9550, is also being investigated in a phase 1 trial, with the planning for a phase 2 trial underway

Cells were then fixed with 3% paraformaldehyde and permeabilized with 0.5% Triton X-100 (#ST795, Beyotime Biotechnology, Shanghai, China)

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Therefore, ARSs are closely related to immune cell maturation, transcription, recruitment, and activation, indicating that these molecules play a crucial role in the development of immune cells