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De Rosa et al., 2000)

It doesn't directly modulate hormones

Research over the past 50 years has consistently demonstrated that byproducts released from smoking tobacco products, such as cigarettes, cause permanent cellular and molecular alterations, which lead to cancer (180)(181)(182)

Abstract The glymphatic system, a network of perivascular channels in the brain, clears toxins and metabolic products such as amyloid- (A), supporting cognitive function and preventing neurodegenerative diseases

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