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c) Ferroptosis in Radiation-Induced Digestive Injury Ferroptosis is an iron-dependent type of programmed cell death initiated by lipid peroxide accumulation and depletion of plasma membrane polyunsaturated fatty acids (199)

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536 When monocytes are stimulated with Mycobacterium bovis BCG cell wall, they induce ZIP8 expression, suggesting that extracellular zinc can be drawn in to fuel the hosts zinc poisoning strategy

GSH biosynthesis requires adequate amounts of cysteine, glutamate, and glycine to maintain appropriate levels, and each of these intersect at metabolic centers that mirror sulfur and nitrogen metabolism, one-carbon metabolism, and overall energy levels in a tissue [36]