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Medicine 98 , e15278 (2019)

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The Kyn-AhR axis additionally polarizes macrophages toward M2 phenotypes and expands Treg populations (291), while AhR blockade in AOM/DSS models reverses TAM polarization, suppresses Tregs, and enhances CD8 + T cell infiltration to ameliorate colitis-associated carcinogenesis (292)

The kinetics of mitochondrial matrix Ca 2+ accumulation is delayed by seconds compared to the rapid increases in cytosolic Ca 2+ in response to glucose (Waldeck-Weiermair et al., 2012)

It has a relapse rate that depends on the dose of radioiodine which is administered