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By contrast, a 17-g increase in fat intake and a 50-g increase in carbohydrate intake was associated with a higher likelihood of wrinkles and skin atrophy.4 Discussion Demand for skin antiaging therapies is high and expected to increase.15 The use of oral supplements and systemic drugs to fight skin aging is an attractive option, as it would eliminate or reduce the need for topical treatments or invasive or minimally invasive procedures, which can be costly and are not without adverse effects

But the key to making them profitable, sustainable, and scalable lies in the systems that support them

The peptide has been shown to promote fat reduction, specifically targeting visceral fat, which is associated with obesity-linked comorbidities such as cardiovascular disease and type 2 diabetes (Vanhee et al., 2014

Based on the outcome of the BLOOM (46) and BLOSSOM trials (47), in 2012 the FDA approved lorcaserin as an addition to a reduced-calorie diet and exercise for eligible patients (48)

doi: 10.1093/nar/gkw952