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Prom-u-thai, C., Rashid, A., Ram, H., Zou, C., Guilherme, L

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Four weeks of moderate-intensity treadmill exercise significantly inhibited the activation of the STING signaling pathway in the damaged cortex of traumatic brain injury mice, downregulated the expression of TFR1, FTH, and ACSL4, upregulated FPN, System Xc , GPX4, and GSH expression, and reduced levels of 4-HNE, MDA, and Fe 2+

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The gastrocnemius muscle in SS-31-treated aged mice showed significantly greater mass compared to untreated age-matched controls, and this increased mass translated to enhanced functional capacity during exercise testing