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124 Aged NK cells exhibit reduced degranulation and impaired perforin secretion, which may be linked to alterations in Ca-dependent exocytosis regulated by Munc13-4, a key protein in NK cell cytotoxic granule release

This occurs through contamination of the conjunctivae, abrasions in the mucous membranes of the mouth, or the louse bite site

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We recently published that wild-type (WT), human parkin can act as a redox state-sensing and redox state-effecting protein