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Prior to analysis, data were subject to outlier detection using an R implementation (available on our Mendeley data site) of the ROUT method (Motulsky and Brown, 2006), using a highly conservative threshold of Q = 0.1

1 H NMR (400 MHz, DMSO-d6) = 10.49 (s, 1H), 8.67 (dd, J = 5.2, 1.8 Hz, 1H), 8.00 (td, J = 7.7, 1.9 Hz, 1H), 7.92 7.83 (m, 2H), 7.66 (d, J = 8.1 Hz, 1H), 7.51 (ddd, J = 7.3, 4.8, 1.1 Hz, 1H), 7.06 6.89 (m, 2H)

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Some mild soreness, swelling, or bruising at the injection site is completely normal for the first few days and can be managed with ice packs and rest

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